Our group uses mathematical methods to understand cardiac electrophysiology, especially the arrhythmias Atrial Fibrillation and Ventricular Fibrillation, the leading cause of sudden cardiac death. We use mathematical analyses and very large-scale computer simulations using our Virtual Heart Model, a 50 million variable supercomputer model of the electrophysiology of the heart.
The Department of Integrative Biology and Physiology (formerly the Department of Physiological Science) is dedicated to explaining the function of complex biological systems, in cells, organs, and individuals. The recent rapid advances in molecular and cell biology and genetics, including the sequencing of numerous genomes, has provided an unprecedented opportunity to use this new information to understand how the genes interact to produce emergent phenotypes in complex systems. The research of our faculty spans many levels. We use approaches that range from RNA interference to ion channel electrophysiology to genetic intervention in behavior to mathematical modeling to robotics, all to make sense of sensory, motor, endocrine, and cardiovascular systems.
At the undergraduate level, the Department of Integrative Biology and Physiology offers the B.S. degree in Physiological Science, and contributes strongly to the
Interdepartmental Undergraduate Program in
Neuroscience. The Department also offers a 2-year research-oriented M.S. program in Physiological Science. Ph.D. students in the Department come from a variety of interdepartmental programs, including, the Ph.D. Program in Molecular, Cellular, and Integrative Physiology, and the Interdepartment Ph.D. Program in Neuroscience.